Abstract

REYES LLERENA, Gil Alberto et al. Tomography by emission of positrons in the diagnosis of sarcoidosis and Löfgren's syndrome. Rev Cuba Reumatol [online]. 2020, vol.22, suppl.1  Epub May 15, 2021. ISSN 1817-5996.

Sarcoidosis is a multisystemic, non-caseating granulomatous disease of unknown cause that involves the lung and the mediastinal lymph nodes in between 90% and 95% of cases. It can also affect other organs, such as the salivary glands, skin, eyes, liver, spleen, heart, bones, and central nervous system. Thoracic involvement represents the main cause of morbidity and mortality in patients with this entity, which occurs in about 10 / 100,000 people a year. Our study aimed to present a 45-year-old patient treated for presenting clinical, paraclinical and radiological manifestations that allow the diagnosis of an acute form of sarcoidosis to be established without confirming by histological study. Its clinical form of expression showed the presence of Löfgren's syndrome with bilateral mediastinal widening due to hilar lymphadenopathy, febrile syndrome, erythema nodosum, and acute arthritis in the lower limbs, which 20-30% of patients with sarcoidosis develop. A positron emission tomography scan was performed and its results offered us diagnostic elements typical of a pulmonary inflammatory process far from the characteristics of a malignant neoplastic process.

Keywords : sarcoidosis; bilateral hilar lymphadenopathy; erythema nodosum; Löfgren's syndrome; PET-CT.

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