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On-line version ISSN 2221-2434
Abstract
RODRIGUEZ JIMENEZ, Ailed; FARDALES RODRIGUEZ, Raikel; TOLEDO RODRIGUEZ, Enrique and QUINTANA CANIZAREZ, Guillermo. Leuko-glycemic Index as a Prognostic Factor after Acute Myocardial Infarction with ST-segment Elevation. Rev. Finlay [online]. 2019, vol.9, n.2, pp. 97-107. Epub Aug 02, 2019. ISSN 2221-2434.
Foundation:
blood glucose and leukocyte count at admission have shown prognostic significance in patients with myocardial infarction. Leuko-glycemic index is a recently proposed marker as a predictor of mortality.
Objective:
to evaluate the usefulness of the leuko-glycemic index in the stratification of the risk of in-hospital death after STEMI.
Method:
a prospective observational study was conducted which included all patients admitted consecutively with a diagnosis of acute myocardial infarction with ST segment elevation and Killip> I class, from January 2012 to June 2015 at the Provincial University Hospital Camilo Cienfuegos Gorriarán. Clinical, laboratory and echocardiographic data were collected and the prognostic implication of the leuko-glycemic index in in-hospital mortality was determined through binary logistic regression. The studied variables were: age, sex and color of the skin, medical history and cardiovascular risk factors, clinical data such as systolic and diastolic blood pressure as well as heart rate at admission.
Results:
LGI was a predictor of mortality in both diabetic and non-diabetic patients (c = 0.673 and c = 0.707) respectively. There was a positive correlation between the Killip class and the leuco-glycemic index (r: 0.471 p <0.001). The 75th percentile showed an acceptable sensitivity and good specificity as a predictor of complications and mortality after STEMI.
Conclusions:
the leuko-glycemic index in the course of an acute myocardial infarction can be associated with a higher in-hospital mortality. Its detection would be useful in the prognostic stratification of acute coronary syndrome.
Keywords : leukocyte count; blood glucose; prognosis; st elevation myocardial infarction.