SciELO - Scientific Electronic Library Online

 
vol.11 issue1Mortality Prognostic Factors in Patients with Cutaneous Malignant MelanomaPrevention of the Renal Chronic Damage: a Priority from Childhood author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Finlay

On-line version ISSN 2221-2434

Abstract

RODRIGUEZ NUNEZ, Axana; CALA FERNANDEZ, Jorge; CRUZ VADELL, Haydee  and  MONTOYA DELER, Miguel Ángel. Oxidative Stress Markers in Patients with Metabolic Syndrome. Rev. Finlay [online]. 2021, vol.11, n.1, pp.23-30.  Epub Mar 31, 2021. ISSN 2221-2434.

Background:

oxidative stress is the balance alteration existing in the body between the action of oxidizing agents. Oxidative stress plays an important role in the pathogenesis of the metabolic syndrome because it affects the function of pancreatic beta cells and alters glucose transport in muscle and adipose tissue.

Objective:

to characterize a population with a metabolic syndrome diagnosis, according to biochemical and anthropometric variables between 2015-2016.

Methods:

a descriptive and cross-sectional study was carried out in patients with a diagnosis of metabolic syndrome belonging to the Julián Grimau and Carlos Juan Finlay health areas of Santiago de Cuba, in the period between 2015-2016. The variables analyzed were: age, sex, presence of arterial hypertension, triacylglycerides, glycemia, anthropometric variables, levels of oxidative markers for protein and lipids, defense marker against oxidative stress. The sample of 119 patients, obtained through simple random sampling. Data processing was performed using SPSS 20.0. For statistical tests, a p <0.05 and a 95 % confidence level were used.

Results

the age groups of 60 to 69 years, female sex, overweight and hypertensive patients predominated in the study patients, in addition to altered levels of abdominal circumference, glycemia, triglycerides, HDL-C.

Conclusions

oxidative stress appear in a remarkable way in these patients, with a significant increase in metabolites product of molecular oxidation and decrease in antioxidant systems in relation to the reference values, for which a statistically significant difference was found between these values.

Keywords : biomarkers; oxidative stress; metabolic syndrome.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )