Abstract

RODRIGUEZ AMADO, Jesús Rafael et al. Composición química y actividad larvicida de un extracto de marañón frente a larvas de mosquitos. Rev Cub Quim [online]. 2017, vol.29, n.3, pp. 330-340. ISSN 2224-5421.

The goal of this work is to evaluate the chemical composition and the larvicidal activity of an extract from the nutshell (Anacardium occidentale L.) against Aedes aegypti and Culex quinquefasciatus larvae. A Hydro-ethanolic extract was prepared by maceration using 1 g of cashew nutshell in 3 mL of ethanol 70 %. The larvicidal effect and the acetylcholinesterase inhibitory activity of the extract were evaluated. The extract content includes phenolic compounds, coumarins, quinones, anthocyanidins, triterpenes, steroids, flavonoids, saponins, lipid compounds, aliphatic acids, and terpenoids. The larvicidal activity of the extract (LC50) for A.aegypti was 35,81 ppm and 40,21 ppm for A. aegypti (Macapá and Rockefeller strains), and 21,47 ppm for C.quinquefasciatus. The IC50 for the AChE inhibitory test was 43,27 ± 2,22 ppm. The evaluated extract presents a good AChE inhibitory activity and a potent larvicidal activity. The larvicidal effect could be associated with the AChE inhibitory activity of the extract.

Keywords : larvicidal activity; nutshell ethanolic extract; mosquitoes.

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