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Acta Médica del Centro

On-line version ISSN 2709-7927

Abstract

GARCIA GOMEZ, Dianiley  and  AGUIAR DIAZ, Emileydi. Characterization of Pseudomonas aeruginosa in the Angiology Department. Acta méd centro [online]. 2022, vol.16, n.1, pp. 46-57.  Epub Mar 31, 2022. ISSN 2709-7927.

Introduction:

it has been observed the emergence of multidrug-resistant strains of Pseudomonas aeruginosa on a global scale during the last decades. This opportunistic pathogen, widely associated with healthcare-associated infections, produces mechanisms of resistance to various antibiotics.

Objective:

to enumerate known risk factors of patients and describe the resistance pattern of Pseudomonas aeruginosa to antimicrobials.

Methods:

a descriptive, cross-sectional study was carried out in the Angiology Service of the “Camilo Cienfuegos” Hospital from Sancti Spíritus between July 1st and December 31st, 2017 about Pseudomonas aeruginosa isolates in purulent samples from patients with healthcare-associated infections. The population was 47 samples. The automated Vitek® 2 Compact system was used to confirm the diagnosis and determine antimicrobial susceptibility to 13 antibiotics tested.

Results:

the main known risk factors found in the patients were type 2 diabetes mellitus and chronic arterial insufficiency. Resistance was maintained to B-lactam antibiotics, including carbapenemics in more than 50%; however, low levels of resistance to aminoglycosides, fluoroquinolones, tigecycline and colistin were maintained.

Conclusions:

type 2 diabetes mellitus was the main risk factor in patients admitted to the Angiology Department for contracting a healthcare-associated infection due to Pseudomonas aeruginosa, B-lactams were highly resistant and colistin may be a possible treatment option.

Keywords : Pseudomonas aeruginosa; antimicrobial resistance; multi-resistance; resistance phenotypes.

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