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Revista Cubana de Medicina Militar

On-line version ISSN 1561-3046

Abstract

VEGA CANDELARIO, Rodolfo  and  VEGA JIMENEZ, Junior. Transient acute renal failure after coronary thrombolysis with streptokinase. Rev Cub Med Mil [online]. 2021, vol.50, n.2  Epub Aug 01, 2021. ISSN 1561-3046.

Introduction:

There are currently more than 150 medications related to the appearance of rhabdomyolysis and transient acute renal failure. Streptokinase can be one of them.

Objective:

Presenting a case the administration of streptokinase as a possible cause of acute, transient renal failure.

Case report:

A 38-year-old patient with a previous health history and 81 mg creatinine per liter days before admission, suffers acute myocardial infarction and after streptokinase thrombolysis he suffers severe muscle pain, nausea, vomiting, severe low back pain, creatinine ascends progressively and progressive oligoanuria that evolves until two weeks when it begins to return. At 21 days with 116 mg creatinine per liter, coronary angiography was performed with normal coronaries.

Comments:

The causes of transient acute renal failure may be rhabdomyolysis associated with abnormalities of the metabolism of ATP and immune disorders, caused by the administration of streptokinase. His coronary angiography was completely normal.

Keywords : therapy thrombolytic; streptokinase; renal intense lesion; infarct of the myocardium.

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